Pitfalls in developmental diagnosis.

Migraine: pitfalls in the diagnosis.

Although the understanding of the pathophysiology and the pharmacology of migraine has exploded there are still many pitfalls that may occur in the clinical assessment and management of migraine. This may prevent the patient from receiving optimal treatment. A diagnosis of migraine may be missed in the presence of other headache types that occur more frequently than migraine. Also, migraine may...

Pitfalls in the Modeling of Developmental Systems

Computational models of development aim to describe the mechanisms that underlie the acquisition of new skills or the emergence of new capabilities. The strength of a model is judged by both its ability to explain the phenomena in question as well as its ability to generate new hypotheses, generalize to new situations, and provide a unifying conceptual framework. Although often constructed usin...

ALS: pitfalls in the diagnosis.

Pitfalls in neuroendocrine tumor diagnosis

Carcinoids, originating from cells of the diffuse endocrine system (DES), account for 0.7% of all malignancies and are characterized by a slow growth rate and the presence of nonspecific signs and symptoms often making their detection rather difficult. Gastroente ropancreatic neuroendocrine tumors (GEP-NETs) represent the majority (~70%) of DES tumors. Historically they account for about 2% of ...

Neuroanatomy of developmental dyslexia: Pitfalls and promise.

Investigations into the neuroanatomical bases of developmental dyslexia have now spanned more than 40 years, starting with the post-mortem examination of a few individual brains in the 60s and 70s, and exploding in the 90s with the widespread use of MRI. The time is now ripe to reappraise the considerable amount of data gathered with MRI using different types of sequences (T1, diffusion, spectr...